Ushma Neill with the Journal of Clinical Investigation Series, Conversations with Giants in Medicine met Dr. Elias Zerhouni at the Lasker Awards in September of 2023 and jumped at the opportunity to be able to spend an hour with him. Zerhouni, who is Professor Emeritus at Johns Hopkins University and Vice Chairman and President of OPKO Health, is a radiologist by training, who focused much of his research on CT and MRI-based imaging methods to diagnose cancer and cardiovascular diseases. He notably served as the director of the US National Institutes of Health from 2002 to 2008 and later as president of global research and development at Sanofi.
In this episode, Ushma Neill speaks with physician and geneticist Dr. Funmi Olopade. Dr. Olopade is the founding director of the Center for Clinical Cancer Genetics and Global Health at the University of Chicago. Olopade's research is focused on gaining a better understanding of the root causes and genomic basis of cancer in diverse populations. She is internationally renowned for her work in inherited cancer syndromes and for her clinical expertise in early detection and prevention of breast cancer in high-risk women.
A committed champion of vaccines and vaccine diplomacy, Dr. Peter Hotez is the Dean of the National School of Tropical Medicine and Professor of Pediatrics and Molecular Virology and Microbiology at the Baylor College of Medicine. As codirector of the Texas Children’s Hospital Center for Vaccine Development, Hotez has led the development and clinical trials of low-cost vaccines for hookworm infection, schistosomiasis, leishmaniasis, Chagas disease, and various coronaviruses. His persistence in the face of online and in-person harassment is impressive. This is an interview with Dr. Hotez from a stop on his book tour at Memorial Sloan Kettering Cancer Center on September 20, 2023.
In this episode, Ushma Neill interviews Elizabeth Jaffee, the Johns Hopkins–based oncologist and immunologist who led the clinical development of a first-gen cancer vaccine for pancreatic cancer and continues to use innovative approaches to identify the complex signaling pathways in tumor cells, the microenvironment, and the immune system toward the generation of cancer immunotherapies. All the while she's been a leader at the local, national, and international level, and currently is the chair of President Biden's Cancer Panel.
In this episode, Ushma Neill interviews the physician scientist and gene therapy, pioneer Dr. Katherine High. After a long career as an academic hematologist, first at the University of North Carolina, then at the University of Pennsylvania and HHMI, Kathy transitioned to a role in industry, first at Spark Therapeutics, then at ASK Biopharma where she led the first FDA approval for gene therapy for a genetic disease.